This is a list of hot sauces that appeared in Season 4 of Hot Ones:
| No. | Sauce | Scoville units |
|---|---|---|
| 1 | Valentina Black Label | 2,100 |
| 2 | Crystal | 3,000 |
| 3 | Secret Aardvark | 5,000 |
| 4 | Queen Majesty – Scotch Bonnet and Ginger | 9,000 |
| 5 | Hot Ones – Fiery Chipotle | 15,600 |
| 6 | Dirty Dicks | 21,000 |
| 7 | Zombie Apocalypse Ghost Chili Sauce | 100,000 |
| 8 | Da' Bomb Beyond Insanity | 135,600 |
| 9 | Blair's Mega Death Sauce | 550,000 |
| 10 | The Last Dab | 2,000,000+ |