This is a list of guest stars who appeared in Season 3 of Hot Ones:
| Guest star | Appears in |
|---|---|
| Padma Lakshmi | Episode 1 |
| Joey "CoCo" Diaz | Episode 2 |
| Danny Brown | Episode 3 |
| Ricky Gervais | Episode 4 |
| Charlie Day | Episode 5 |
| Mac DeMarco | Episode 6 |
| Russell Brand | Episode 7 |
| Charlie Sloth | Episode 8 |
| Kyle Kinane | Episode 9 |
| Dax Shepard | Episode 10 |
| H3H3 Productions | Episode 11 |
| Keke Palmer | Episode 12 |
| Charlamagne Tha God | Episode 13 |
| DJ Snake | Episode 14 |
| Guy Fieri | Episode 15 |
| Kevin Love | Episode 16 |
| Neil deGrasse Tyson | Episode 17 |
| Thomas Middleditch | Episode 18 |
| Andy Cohen | Episode 19 |
| Tom Arnold | Episode 20 |
| Coyote Peterson | Episode 21 |
| Nick Kroll | Episode 22 |
| Superfan Brett Baker | Episode 23 |
| Seth Rogen and Dominic Cooper | Episode 24 |