This is a list of guest stars who appeared in Season 13 of Hot Ones:
| Guest star | Appears in |
|---|---|
| Jessica Alba | Episode 1 |
| Ronda Rousey | Episode 2 |
| Naomi Campbell | Episode 3 |
| Matthew McConaughey | Episode 4 |
| Sam Smith | Episode 5 |
| Saweetie | Episode 6 |
| Thundercat | Episode 7 |
| The Undertaker | Episode 8 |
| Lil Nas X | Episode 9 |
| Daniel Radcliffe | Episode 10 |